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    Dr. Santanu Kar Mahapatra's profile

    Name : Dr. Santanu Kar Mahapatra


    Designation : Associate Professor & HOD
    Qualification : M.Sc., PhD
    Subject : Physiology
    Department Name : Paramedical & Allied Health Science
    Email ID : sailar.santanu@gmail.com
    Address : Egra, Municipality, Purba Medinipur - 721429

    Degree name Board / University Subject/Field of Specialization Year of passing/awarded
    M. Sc. in Human Physiology Vidyasagar University Immunology and Microbiology 68 2005
    Ph.D. Vidyasagar University Immunotoxicology and Pharmacology 0 2010
    Secondary WBBSE Bengali, English, Life Science, Physical Science, Mathematics, History, Geography 80.4 1998
    H.S. WBCHSE Bengali, English, Biology, Physics, Mathematics 70.4 2000
    B.Sc. (Hon's) Vidyasagar University Physiology 61 2003
    • Worked as Assistant Professor - Research, SCBT, SASTRA Deemed University (2012-2020)
    • Worked as Research Associate III, Bose Institute, Kolkata (2010-2012)
    Field of Specialization Research Area/ Areas of Interest
    Immunology Macrophage polarization, Immune metabolism, TLRs
    Physiology Infectious Disease (Leishmania, Tuberculosis, Malaria)
    Sl no. Subject
    1 Physiology, Immunology, Instrumentation, Pathology, Forensic Sciences, Nutritional Genomics, GM Foods

    International Publication


    Sl no. Title Author Journal Name ISBN/ISSN Page No/Internet DOI Impact Factor Year Link
    1 Ursolic Acid Reduces Parasite Burden Through Th-1 Mediated Immunomodulation in Experimental Visceral Leishmaniasis. Mandal S, Biswas A, Bakshi U, Pramanik M, Ali MS, Majumdar S, Kar Mahapatra S, Jawed JJ. Journal of the American Nutrition Association, 2026 Jan;45(1):75-88 2769-7061 https://doi.org/10.1080/27697061.2025.2536301 2.6 2026
    2 Review on macrophage polarization during visceral leishmaniasis and impact of glycoprotein 6. Datta N, Dasmahapatra S, Pramanik M, Mahapatra SK Glycoconjugate Journal, 2026 Jan 9;43(1):7. 1573-4986 https://doi.org/10.1007/s10719-025-10206-w 3.1 2026
    3 Updated review on modern context of drug resistance in visceral leishmaniasis, Pramanik M, Datta N, Dasmahapatra S, Guchhait S, Khas SK, Kar Mahapatra S European Journal of Pharmacology, 2026;1029:179048. 1879-0712 https://doi.org/10.1016/j.ejphar.2026.179048 5.7 2026
    4 Synergistically crosslinked alginate-CMC hydrogel reinforced with natural fibre for enhanced mechanical and antibacterial activity Sahoo S, Kumar A, Negi K, Mahapatra SK, Sahu SK European Polymer Journal, 2026, 253, 2026, 114759 1873-1945 https://doi.org/10.1016/j.eurpolymj.2026.114759 6.3 2026
    5 MicroRNA-221–3p targets the cell cycle regulator gene CDKN1B to suppress the cytotoxic effects of manganese in human pulmonary epithelial cells Punniyasekaran Y, Pal HA, Dasmahapatra S, Kar Mahapatra S, Rajasekaran S. Journal of Trace Elements in Medicine and Biology, 2026, 95, 2026, 127872, 1878-3252. https://doi.org/10.1016/j.jtemb.2026.127872 3.3 2026
    6 The Biocide Triclosan Drives the Inflammatory Responses in Epithelial Cells and Macrophages via ROS-Mediated Activation of ERK/NF-κB Signaling Pathways Das A, Bhandari S, Datta N, Mishra S, Mahapatra SK, Rajasekaran S Journal of Applied Toxicology, 2026 Apr 9. 1099-1263 https://doi.org/10.1002/jat.70202 2.8 2026
    7 Isolated glycoprotein STK11 from the nutshell of Cocos nucifera L. modulated macrophage polarization to prevent the Mycobacterium tuberculosis bacilli growth in J774A.1 macrophage Samanta A, Datta N, Pramanik M, Srinivasan S, Kar Mahapatra S Microbial Pathogenesis, 2026, Vol 215, 108456 1096-1208. https://doi.org/10.1016/j.micpath.2026.108456. 3.5 2026
    8 Protective role of butylated hydroxyanisole (BHA) and hydroxytoluene (BHT) against oxidative stress-induced inflammatory response in carbon tetrachloride-induced acute hepatorenal toxicity 9. Dassarma B, Mahapatra SK, Nandi DK, Gangopadhyay S, Samanta S Archives of Physiology and Biochemistry, 2025 Oct;131(5):728-735. 1744-4160 https://doi.org/10.1080/13813455.2025.2493105 2.7 2025
    9 Activation of ERK/NF-kB Pathways Contributes to the Inflammatory Response in Epithelial Cells and Macrophages Following Manganese Exposure. Gandhi D, Bhandari S, Maity S, Mahapatra SK, Rajasekaran S. Biol Trace Elem Res. 6 doi: 10.1007/s12011-024-04154-z. 3.9 2024
    10 Liposomal dual delivery systems in visceral leishmaniasis enhance the synergistic effects of combination therapy: A promise for the future. Hazra R, Kar A, Kar Mahapatra S. Asian Pacific Journal of Tropical Medicine 47-60 10.4103/apjtm.apjtm_567_23. 3.1 2024
    11 Macrophage polarization or repolarization in tuberculosis. Samanta A, Maity S, Hazra R, Jayaraman A, Mahapatra SK Asian Pacific Journal of Tropical Medicine XXX XXX 3.1 2024
    12 Partial characterization of purified glycoprotein from nutshell of Arachis hypogea L. towards macrophage activation and leishmaniacidal activity. Srinivasan S, Charan Raja MR, Kar A, Ramasamy A, Jayaraman A, Vadivel V, Kar Mahapatra S. Glycoconj J. 1-17 10.1007/s10719-022-10096-2. 3.009 2023
    13 Isolation and characterization of glycoprotein (CNP) isolated from Cocos nucifera L. nutshell and its immunomodulatory role on macrophage activation Srinivasan S, Jayaraman A, Ramasamy K, Charan Raja M.R, Kar Mahapatra S. Journal of Functional Foods 105380 https://doi.org/10.1016/j.jff.2022.105380 5.223 2023
    14 Unwinding the mechanism of macrophage repolarization potential of Oceanimonas sp. BPMS22-derived protein protease inhibitor through Toll-like receptor 4 against experimental visceral leishmaniasis. Jayaraman A, Srinivasan S, Uppuluri KB, Kar Mahapatra S. Front Cell Infect Microbiol 2023 10.3389/fcimb.2023.1120888 6.073 2023
    15 A brief report on eugenol oleate is an oral immunomodulatory molecule against Visceral Leishmaniasis 13. Hazra R, Charan Raja MR, Kar Mahapatra S Indian Journal of Physiology and Allied Sciences, 2023, 75(02), 84–88 0367-8350 https://doi.org/10.55184/ijpas.v75i02.11 2023
    16 Vitexin isolated from Prosopis cineraria leaves induce apoptosis in K-562 leukemia cells via inhibition of the BCR-ABL-Ras-Raf pathway. 4. Sarkar MK, Kar A, Jayaraman A, Kar Mahapatra S, Vadivel V. J Pharmacy Pharmacol 2022; 74(1):103-111. 2042-7158 10.1093/jpp/rgab085 2.571 2022
    17 Oceanimonas sp. BPMS22-derived protein protease inhibitor induces anti-leishmanial immune responses through macrophage M2 to M1 repolarization. Jayaraman A, Srinivasan S, Kar A, Harish BS, Charan Raja MR, Uppuluri KB, Kar Mahapatra S*. Int Immunopharmacol 112:109281. 10.1016/j.intimp.2022.109281 5.71 2022
    18 Anti-virulence properties of catechin-in-cyclodextrin-in-phospholipid liposome through down-regulation of gene expression in MRSA strains. 18. Sinsinwar S, Jayaraman A, Kar Mahapatra S, Vellingiri V Microbial Pathogenesis, 2022, 167, 105585 1096-1208 https://doi.org/10.1016/j.micpath.2022.105585 3.8 2022
    19 Dynamicity in Host Metabolic Adaptation Is Influenced by the Synergistic Effect of Eugenol Oleate and Amphotericin B During Leishmania donovani Infection In Vitro. Kar A, Jayaraman A, Kumar A and Kar Mahapatra S*. Front. Cell. Infect. Microbiol. 2021, 11:709316 2235-2988 10.3389/fcimb.2021.709316 5.293 2021
    20 Oral combination of eugenol oleate and miltefosine induce immune response during experimental visceral leishmaniasis through nitric oxide generation with advanced cytokine demand. Kar A, Charan Raja MR, Jayaraman A, Srinivasan S, Debnath J, Kar Mahapatra S* Cytokine 146 (2021) 155623. 1043-4666 10.1016/j.cyto.2021.155623 3.861 2021
    21 Anti-asthmatic effects of tannic acid from Chinese natural gall nuts in a mouse model of allergic asthma. Rajasekar N, Sivanantham A, Kar A, Mukhopadhyay S, Kar Mahapatra S, Paramasivam SG, Rajasekaran S. Int Immunopharmacol. 98 (2021) 107847. 1878-1705 10.1016/j.intimp.2021.107847 4.932 2021
    22 Synergic effect of eugenol oleate with amphotericin B augments anti-leishmanial immune response in experimental visceral leishmaniasis in vitro and in vivo Kar A, Jayaraman A, Charan Raja MR, Srinivasan S, Debnath J, Kar Mahapatra S* Int Immunopharmacol. 2021; 91:107291. 1878-1705 10.1016/j.intimp.2020.107291 4.932 2021
    23 Apoptotic mechanism of myricitrin isolated from Madhuca longifolia leaves in HL-60 leukemia cells. Sarkar MK, Kar A, Jayaraman A, Shanmugam K Vadivel V., Kar Mahapatra S*. Molecular Biology Reports. (2021); 48(6): 5327-5344. 1573-4978 10.1007/s11033-021-06500-z 2.316 2021
    24 Pharmacokinetic properties and anti-proliferative mechanisms of vanillin against acute lymphoblastic leukemia (Jurkat) cells. Sarkar MK, Kar A, Jayaraman A, Kar Mahapatra S*, Vadivel V. South African Journal of Botany 142 (2021) 82-87. 0254-6299 10.1016/j.sajb.2021.06.016 2.315 2021
    25 Oral administration of eugenol oleate cures experimental visceral leishmaniasis through cytokines abundance. Charan Raja MR, Kar A, Srinivasan S, Chellappan D, Debnath J, Kar Mahapatra S*. Cytokine.145 (2021) 155301. 1043-4666 10.1016/j.cyto.2020.155301 3.861 2021
    26 Production enhancement of an anticoagulant trypsin inhibitor from Oceanimonas sp. BPMS22 and its anti‑cancer activity. Harish BS, Charan Raja MR, Kar Mahapatra S*, Uppuluri KB*. International Journal of Peptide Research and Therapeutics. 2021. 27, 197–208. 1573-3149 doi.org/10.1007/s10989-020-10078-8 1.931 2021
    27 Lead Generation for Human Mitotic Kinesin Eg5 using Structure-based Virtual Screening and Validation by in vitro and Cell-based Assays. Makala H, Alexandar SP, Nagarajan D, Kar Mahapatra S, Ulaganathan V Curr Comput Aided Drug Des. 2021;17(6):759-772 1573-4099 10.2174/1573409916666200722141218 1.606 2021
    28 Tannic acid alleviates experimental pulmonary fibrosis in mice by inhibiting inflammatory response and fibrotic process. 10. Rajasekar N, Sivanantham A, Kar A, Kar Mahapatra S, Ahirwar R, Thimmulappa RK, Paramasivam SG, Subbiah R. Inflammopharmacology. 2020 Oct;28(5):1301-1314. 1568-5608 10.1007/s10787-020-00707-5 4.473 2020
    29 Oxidative stress mediated cytotoxicity in leukemia cells induced by active phyto-constituents isolated from traditional herbal drugs of West Bengal Sarkar MK, Kar Mahapatra S,** Vadivel V.* J Ethnopharmacol. 251 (2020) 112527. 0378-8741 10.1016/j.jep.2019.112527 4.36 2020
    30 Tannic acid prevents macrophage-induced pro-fibrotic response in lung epithelial cells via suppressing TLR4-mediated macrophage polarization. Sivanantham A, Pattarayan D, Rajasekar N, Kannan A, Loganathan L, Bethunaickan R, Kar Mahapatra S, Palanichamy R, Muthusamy K, Rajasekaran S. Inflamm Res. 68(12):1011-1024. 1023-3830 10.1007/s00011-019-01282-4 4.575 2019
    31 Genome‐wideanalysis revealsmiR‐3184‐5pandmiR‐181c‐3p as a critical regulator for adipocytes‐associated breast cancer. Rajarajan D, Selvarajan S, Charan Raja MR, Kar Mahapatra S, Kasiappan R. J Cellular Physiology. 34(10):17959-17974. 1097-4652 10.1002/jcp.28428 6.384 2019
    32 Investigation of phytochemical constituents of anti-leukemic herbal drugs used by the traditional healers of Purulia, Birbhum and Bankura districts of West Bengal. Sarkar MK, Vadivel V, Charan Raja MR, Kar Mahapatra S* Nat Prod Res. 34(23): 3388-3393. 1478-6419 10.1080/14786419.2019.1566818. 2.861 2019
    33 Tannic acid protects against experimental acute lung injury through down-regulation of TLR4 and MAPK Sivanantham A, Pattarayan D, Bethunaickan R, Kar A, Kar Mahapatra S, Thimmulappa RK, Palanichamy R, Rajasekaran S J Cellular Physiology. 234(5):6463-6476 1097-4652 10.1002/jcp.27383 6.384 2019
    34 Potential anti-proliferative activity of AgNPs synthesized using M. longifolia in 4T1 cell line through ROS generation and cell membrane damage Sarkar MK, Vadivel V, Charan Raja MR, Kar Mahapatra S* J Photochem Photobiol B: Biology, 186: 160-168 1011-1344 10.1016/j.jphotobiol.2018.07.014 6.252 2018
    35 Eugenol derived immunomodulatory molecules against visceral leishmaniasis. Charan Raja MR, Velappan AB, Chellappan D, Debnath J,* Kar Mahapatra S,*. Eur J Med Chem., 139: 503-518. 0223-5234 10.1016/j.ejmech.2017.08.030 6.514 2017
    36 ApAGP Fabricated Silver Nanoparticles Induce Amendment of Murine Macrophage Polarization. 19. Charan Raja MR, Vinod Kumar V, Varsha S, Sharmila S, Nivedha R, Roshni M, Subhashree R, Philip Anthony S, Kar Mahapatra S* J Mater Chem B, 5, 3511-3520. 2050-7518 10.1039/C6TB02095J 6.331 2017
    37 Progressive Increase in Point Mutations Associates Chloroquine Resistance: Even After Withdrawal of Chloroquine use in India Das S, Tripathy S, Chattopadhayay S, Das B, Kar Mahapatra S, Hati AK, Roy S. Int J Parasitol–Drugs and Drug Resistance. 7(3):251-261. 2211-3207 10.1016/j.ijpddr.2017.06.002. 4.809 2017
    38 Interaction of cadmium sulfide quantum dots with jacalin for specific recognition of cancer cells. Khan Behlol AA, Charan Raja MR, Kar Mahapatra S, Anbazhagan V J Luminescence, 182, 283–288 0022-2313 10.1016/j.jlumin.2016.10.045 3.599 2017
    39 Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea. Velappan AB, Charan Raja MR, Datta D, Tsai Y, Halloum I, Wan B, Kremer L, Gramajo H, Franzblau SG, Kar Mahapatra S,* Debnath J*. Eur J Med Chem., 125: 825-841. 0223-5234 10.1016/j.ejmech.2016.09.083 6.514 2017
    40 Plant phenyl-propanoids conjugated silver nanoparticles from edible plant Suaeda maritima (L.) Dumort. inhibit proliferation of K562-human myeloid leukemia cells. Narendran R, Shankar S, Charan Raja MR, Brindha P, Kar Mahapatra S*, and Aravind S*. Artif Cells Nanomed Biotechnol; 45(7):1336-1342. 2169-1401 10.1080/21691401.2016.1236803 5.605 2017
    41 Arene Ruthenium (II) Complexes with Chalcone, Aminoantipyrine and Aminopyrimidine Based Ligands: Synthesis, Structure and Preliminary Evaluation of Anti-leukemia Activity Pitchaimani J, Charan Raja MR, Sujatha S, Kar Mahapatra S,* Moon D,* Philip Anthony S* and Madhu V*. RSC Advances, 6, 90982-92. 2046-2069 10.1039/C6RA18504E 3.361 2016
    42 Design, synthesis and in-vitro anti-leukemic evaluation of ferulic acid analogues as BCR-Abl inhibitors Narendran R, Shankar S, Charan Raja MR, Rao HMV, Subhashree R, Venkatasubramanian U, Brindha P, Kar Mahapatra S*, Aravind S*. RSC Advances, 6, 70480-4. 2046-2069 10.1039/C6RA10106B. 3.361 2016
    43 Acetyl shikonin induces IL-12, nitric oxide and ROS to kill intracellular parasite Leishmania donovani in infected host. Charan Raja MR, Sujatha S, Shankar S, Narendran R, Aravind S*, Kar Mahapatra S*. RSC Advances, 6, 61777-61783. 2046-2069 10.1039/C6RA11510A 3.361 2016
    44 Jacalin capped silver nanoparticles minimizes the dosage use of the anticancer drug, shikonin derivatives against human chronic myeloid leukemia Khan Behlol AA, Kar Mahapatra S, Charan Raja MR, Shankar S, Megarajan S, Narendran R, Dash SK, Haldar K, Roy S, Aravind S and Anbazhagan V RSC Advances, 6, 18980-18989 2046-2069 10.1039/C5RA27952F 3.361 2016
    45 Toll-Like Receptor 2 Targeted Rectification of Impaired CD8+ T Cell Functions in Experimental Leishmania donovani Infection Reinstates Host Protection Bandyopadhyay S, Kar Mahapatra S, Paul Chowdhury B, Kumar Jha M, Das S, Halder K, Bhattacharyya Majumdar S, Saha B, Majumdar S. PLOS One., 10(11):e0142800. 1932-6203 10.1371/journal.pone.0142800 3.057 2015
    46 Eugenol: A Versatile Phytomedicine. Charan Raja MR, Varsha S, Sharmila S, Kar Mahapatra S*. Int J Pharmacy Pharmaceutical Sci. 7, 35-40. 0975-1491 0.54 2015
    47 Self-assembled nano fibers of betulinic acid: A selective inducer for ROS/TNFalpha pathway mediated leukemic cell death Dash SK, Chattopadhyay S, Dash SS, Tripathy S, Das B, Kar Mahapatra S, Bag BG, Karmakar P, Roy S. Bioorg Chem., 63:85-100 1090-2120 10.1016/j.bioorg.2015.09.006 5.275 2015
    48 Self-assembled betulinic acid augments immunomodulatory activity associates with IgG response Dash SK, Chattopadhyay S, Tripathy S, Dash SS, Das B, Mandal D, Kar Mahapatra S, Bag BG, Roy S Biomed Pharmacother.75:205-17 1950-6007 10.1016/j.biopha.2015.07.033 6.529 2015
    49 Folate decorated delivery of self assembled betulinic acid nano fibers: A biocompatible anti-leukemic therapy Dash SK, Dash SS, Chattopadhyay S, Ghosh T, Tripathy S, Kar Mahapatra S, Bag BG, Das D, Roy S. RSC Advances. 5, 24144-24157 2046-2069 10.1039/C5RA01076D 3.84 2015
    50 Cobalt oxide nanoparticles induced oxidative stress linked to activation of TNF-α/caspase-8/p38-MAPK signaling in human leukemia cells Chattopadhyay S, Dash SK, Tripathy S, Das B, Kar Mahapatra S, Pramanik P, Roy S J Appl Toxicol., 35(6):603-13. 1099-1263 10.1002/jat.3080 3.446 2015
    51 Double mutation in pfmdr1 gene associates emergence of chloroquine resistant Plasmodium falciparum malaria in Eastern India. Das S, Kar Mahapatra S, Tripathy S, Chattopadhyay S, Dash SK, Mandal D, Das B, Hati AK, Roy S Antimicrob Agents Chemother. 58(10), 5909–15. 1098-6596 10.1128/AAC.02762-14 5.191 2014
    52 Phytopharmacological approach of free radical scavenging and antioxidative potential of eugenol and Ocimum gratissimum Linn Kar Mahapatra S,* Roy S. Asian Pac J Trop Med., 7S1, S391-7 1995-7645 10.1016/S1995-7645(14)60264-9 1.772 2014
    53 A prospective strategy to restore the tissue damage in malaria infection: Approach with chitosan-trypolyphosphate conjugated nanochloroquine in Swiss mice Tripathy S, Das S, Dash SK, Kar Mahapatra S, Chattopadhyay S, Majumder S, Roy S Eur J Pharmacol., 737, 11–21. 1879-0712 10.1016/j.ejphar.2014.04.030 4.432 2014
    54 Chitosan modified cobalt oxide nanoparticles stimulate TNF-α mediated apoptosis in human leukemic cells. Chattopadhyay S, Dash SK, Kar Mahapatra S, Tripathy S, Ghosh T, Das B, Das D, Pramanik P, Roy S J. Biol Inorg Chem. 19, 399–414. 1432-1327 10.1007/s00775-013-1085-2 3.358 2014
    55 A novel chitosan based antimalarial drug delivery against Plasmodium berghei infection Tripathy S, Kar Mahapatra S, Chattopadhyay S, Das S, Dash SK, Majumder S, Pramanik P, Roy S Acta Tropica, 128(3):494–503 1873-6254 10.1016/j.actatropica.2013.07.011 3.112 2013
    56 Miltefosine triggers a strong proinflammatory cytokine response during visceral leishmaniasis: Role of TLR4 and TLR9 Mukherjee AK, Gupta G, Adhikari A, Majumder S, Kar Mahapatra S, Majumdar SB, Majumdar S Int Immunopharmacol. April 12(4): 565–572 1878-1705 10.1016/j.intimp.2012.02.002 4.932 2012
    57 Gutkha chewing induces oxidative disturbances and cellular DNA damage in humans Chakraborty SP, Kar Mahapatra S, Roy S, Roy S. Toxicological and Environmental Chemistry (2):388–402 1029-0486 10.1080/02772248.2011.639942 1.437 2012
    58 In vitro time dependent vancomycin resistant Staphylococcus aureus induced free radical generation and status of antioxidant enzymes in murine peritoneal macrophage. Chakraborty SP, Kar Mahapatra S, Roy S Toxicol Mechanism Method, Jan 22(1):9–22 1537-6524 10.3109/15376516.2011.583296 2.987 2012
    59 Immunomodulatory role of Ocimum gratissimum and ascorbic acid against nicotine-induced murine peritoneal macrophages in vitro. Kar Mahapatra S, Chakraborty SP, Roy S. Oxidative Medicine and Cellular Longevity. December, Volume 2011, Article ID 734319, 11 pages 1942-0994 10.1155/2011/734319 6.543 2011
    60 Prevalence of severe chloroquine resistance associates the point mutation in pfcrt and pfmdrI gene in eastern India Kar Mahapatra S, Chakraborty SP, Das S, Hati AK, Roy S. Asian Pacific Journal of Tropical Disease. Dec 1(4): 263-269 2222-1808 10.1016/S2222-1808(11)60062-5 1.32 2011
    61 Internalization of Staphylococcus aureus in lymphocytes induces oxidative stress and DNA fragmentation: possible ameliorative role of nanoconjugated vancomycin. 45. Chakraborty SP, Kar Mahapatra S, Sahu SK, Das S, Tripathy S, Dash S, Pramanik P, Roy S. Oxidative Medicine and Cellular Longevity. September, Volume 2011, Article ID 942123. 1942-0994 10.1155/2011/942123 6.543 2011
    62 Alteration of immune functions and Th1/Th2 cytokines balance in nicotine-induced murine macrophages: Immunomodulatory role of eugenol and N-acetylcysteine. Kar Mahapatra S, Bhattacharjee S, Chakraborty SP, Majumdar S, Roy S. Int Immunopharmacol. April, 11(4):485–495 1878-1705 10.1016/j.intimp.2010.12.020 4.932 2011
    63 Nanoconjugated vancomycin: new opportunities for the development of anti-VRSA agents Chakraborty SP, Sahu SK, Kar Mahapatra S, Santra S, Bal M, Roy S, Pramanik P. Nanotechnology, March 21:105103. 1361-6528 10.1088/0957-4484/21/10/105103 3.874 2010
    64 Eugenol protects nicotine-induced superoxide mediated oxidative damage in murine peritoneal macrophages in vitro. Kar Mahapatra S, Chakraborty SP, Majumdar S, Bag BG, Roy S. European Journal of Pharmacology, 623(1-3):132–140. 1879-0712 10.1016/j.ejphar.2009.09.019 4.432 2009
    65 Methanol extract of Ocimum gratissimum protects murine peritoneal macrophages from nicotine toxicity by decreasing free radical generation, lipid and protein damage, and enhances antioxidant protection. Kar Mahapatra S, Chakraborty SP, Das S, Roy S. Oxidative Medicine and Cellular Longevity, September, 2(4):222–230. 1942-0994 10.4161/oxim.2.4.9000 6.543 2009
    66 In vitro nicotine induced oxidative stress in mice peritoneal macrophages: a dose dependent approach. Kar Mahapatra S, Das S, Bhattacharjee S, Gautam N, Majumdar S, Roy S. Toxicology Mechanisms and Methods, Feb 19(2):100–108. 1537-6524 10.1080/15376510802255184 2.987 2009
    67 Amelioratory effect of Andrographis paniculata Nees on liver, kidney, heart, lung and spleen during nicotine induced oxidative stress. Neogy S, Das S, Kar Mahapatra S, Mandal N, Roy S. Environmental Toxicology and Pharmacology, 25(3):321–328. 1382-6689 10.1016/j.etap.2007.10.034 4.860 2008
    68 Oxidative stress in lymphocytes, neutrophils, and serum of oral cavity cancer patients: modulatory array of L-glutamine Das S, Kar Mahapatra S, Gautam N, Das A, Roy S. Supportive Care in Cancer, December 15 (12):1399–1405. 1433-7339 10.1007/s00520-007-0266-3 3.603 2007

    National Publication


    Sl no. Title Author Journal Name ISBN/ISSN Page No/Internet DOI Impact Factor Year Link
    1 A brief report on eugenololeate is an oral immunomodulatory molecule against Visceral Leishmaniasis. Hazra R, Charan Raja M.R, Kar Mahapatra S. Indian Journal of Physiology and Allied Sciences 84–88 https://doi.org/10.55184/ijpas.v75i02.11 2023
    Sl no. Scholar name Thesis title Co-Supervisor Status Completion year
    1 Dr. Mamilla R. Charan Raja Eugenol-derived immunomodulatory molecule against experimental visceral leishmaniasis N/A Awarded 2020
    2 Dr. Amrita Kar Study of the anti-leishmanial immune response of eugenol oleate with amphotericin B and miltefosine in experimental visceral leishmaniasis N/A Awarded 2021
    3 Miss Sujatha S Isolation and characterization of biomolecules from agriculture waste product and its effect on macrophage polarization to treat visceral leishmaniasis N/A Awarded 2023
    4 Mr. Adityan J Bioprospecting of PPI from Oceanimonas Sp. BPMS22 and its role on macrophage repolarization in the treatment of Visceral Leishmaniasis. N/A Awarded 2023
    5 Mr. Arijeet Samanta Macrophage polarization during tuberculosis for the implementation of host directed therapy by a novel immunomodulator. N/A Ongoing
    6 Madhusri Pramanik Effect of eugenol oleate against drug resistant Visceral Leishmaniasis N/A Ongoing
    7 Sajal Dasmahapatra Targeted dual drug delivery against experimental Visceral Leishmaniasis N/A Ongoing
    8 Nayanika Datta Study of macrophage repolarization to augment anti-leishmanial immune response by isolated glycoprotein from nutshell of Arachis hypogea L. N/A Ongoing
    Sl no. Project title Worked as Funding Agency Amount in Rs. Duration in years Period Status
    1 Bioprospecting of a protein protease inhibitor from an isolated marine bacterium Oceanimonas Sp. BPMS22 and its role on macrophage repolarization in the treatment of Visceral Leishmaniasis Principal Investigator DBT, Govt. of India 49.932 Lakh 3 2018-2021 Completed
    2 Discovery and development of novel, long-acting anti-leishmanial drugs. Principal Investigator FNDR, India 65.63 Lakh 3 2017-2020 Completed
    3 Study of anti-leishmanial synergic potential of miltefosine and CXCL10 Principal Investigator SERB-Young Scientist Scheme, Govt. of India 24 Lakh 3 2014-2017 Completed
    4 Multicentric project: Comprehensive Tribal TB Management Program for Decentralized TB Care Services. Principal Investigator ICMR-Tb Consortia, Govt. of India 76.93 Lakh 2 2023-2025 Ongoing
    5 Study of the synergic anti-leishmanial effect of eugenol oleate and amphotericin B through liposomal delivery. Principal Investigator ICMR Ad-hoc, Govt. of India 53.79 Lakhs 3 2023-2026 Ongoig
    6 Study of macrophage repolarization to augment anti-leishmanial immune response by isolated glycoprotein from the nutshell of Arachis hypogea L. Principal Investigator SERB, Govt. of India 45.98 Lakh 3 2024-2027 Ongoing
    7 In-vitro efficacy studies of NOVICULE-TA Principal Investigator TECH ATRIOCARE PRIVATE LIMITED 0.25 Lakh 1 2024-2025 Ongoing
    8 Establishment of anti-obesity potentiality of new conjugated fatty acids isolated from marine Phasa fish oil (Setipinna phasa) on in vivo and in vitro model-A Mechanistic study Co-PI ICMR Ad-hoc, Govt. of India 43.79 Lakh 3 2022-2025 Ongoing
    Sl no. Title Organized by Venue Year
    1 Visceral Leishmaniasis: Necessity of Macrophage repolarization SAVEETHA School of Engineering, Institute of Biomedical Engineering Webinar 2021
    2 Eugenol Derived Immunomodulatory Molecules: A Future Prospect against Visceral Leishmaniasis International Conference On Antimicrobial Resistance, organized by CRID, SASTRA Deemed To Be University, Thanjavur SASTRA Deemed To Be University 2018
    3 The promise of Eugenol-Oleate against Visceral Leishmaniasis through modulation of immune responses. CRS Bronze Medal Award Lecture In the One-Day Symposium: Science Beyond Boundary: Invention, Discovery, Innovation and Society “Rasayan 18”. Organized by Chirantan Rasayan Sanstha (CRS) Christ University, Bengaluru. January 29-30, 2024.
    4 2. Anti-Leishmanial Immune Response of Eugenol-Oleate with Amphotericin B in Experimental Visceral Leishmaniasis. International Conference entitled “ Brain Healthcon-2023 “ on the theme " Translation Research for Sustainable Growth on Public Health care'. Dept. of Allied Health Sciences, Brainware University, Kolkata. 8th to 10th December 2023.
    5 3. Eugenol oleate is an oral immunomodulatory molecule against visceral leishmaniasis. Santanu Kar Mahapatra. Dr. Siddhartha Debnath Memorial Oration Lecture, XXXIIIrd Annual Conference of the Physiological Society of India (PSI), the “XXXIIIrd PHYSICON 2022” “Research and Technological Advancement in Health Sciences and Sustainable Development” 3-5 Marc Department of Human Physiology, Vidyasagar University, Paschim Medinipur, West Bengal. 3-5 March 2023
    6 Marine BPMS22-PPI induced TLR-4 dependent macrophage M2 to M1 repolarization augment anti-leishmanial immune responses. Young Scientist Lecture, 5th Annual National Conference MCCCON-2024. Sponsored by SERB and DBT, Govt. of India. Midnapore City College, Paschim Medinipur, West Bengal, India. 4th to 6th February 2024.
    7 Promising role of Nut shell derived Protein in the treatment of Visceral Leishmaniasis. 4th Annual National Conference MCCCON-2023 on Food Informatics: Opportunities and Challenges, Sponsored by SERB and DBT, Govt. of India. Midnapore City College, Paschim Medinipur, West Bengal, India. 4th to 6th February 2023.
    8  Attended “Workshop on GCP guidelines, ICMR National Ethical guidelines 2017 & New drugs and clinical trials rules, 2019 (NDCT rules) Midnapore City College in partnership with ICMR NIHR, Bhubaneshwar Midnapore City College, Paschim Medinipur, West Bengal, India. 6th July 2026
    9 ‘BPMS22-PPI’ skewed M2 to M1 macrophage polarization depending on TLR4 to induce anti-leishmanial immune responses. international conference on “Sustainable Health: Translational Research from Molecules to Behavioural Aspects” Department of Human Physiology Vidyasagar University, Paschim Medinipore, W.B. India Feb 28th to 1st March 2025
    10 The promise of Eugenol-oleate against Visceral Leishmaniasis through modulation of Immune responses 6th Annual National Conference MCCCON-2025 Midnapore City College, Paschim Medinipur, West Bengal, India 4th to 6th February 2025
    • Indian Society of Systems for Science and Engineering (ISSE) (LM05600).
    • Society of Biological Chemist (India) (2564).
    • Indian Science Congress Association (L12490).
    • The Physiological Society of India (PSI-LM867)
    Sl no. Title of the Seminar/Conference/Workshop Year Role Venue Funding agency
    1 National Webinar on “Online education & rural students: implications & It’s limitations” 2021 Participated Webinar N/A
    2 International Webinar on “Current Trends in Neuroimmune Pharmacology” 2021 Participated Webinar N/A
    3 Webinar on "mRNA Technology for Infectious Diseases: Therapeutic Applications and Vaccine Development" 2020 8. Participated Webinar by by ACS N/A
    4 Webinar on “Harnessing the Tumor Immune Microenvironment” 2020 Participated Organized by Cell press N/A
    5 Webinar on “Therapies and Vaccine Development for Emerging and Re-emerging Diseases” 2020 Participated Organized by Cell press N/A
    6 Attended “Workshop on GCP guidelines, ICMR National Ethical guidelines 2017 & New drugs and clinical trials rules, 2019 (NDCT rules) 2026 Participated Midnapore City College in partnership with ICMR NIHR, Bhubaneshwar N/A
    Sl no. Award Name Awarded By Year
    1 CRS Bronze Medal Award Chirantan Rasayan Sanstha (CRS) at Christ University, Bengaluru 2024
    2 Dr. Siddhartha Debnath Memorial Oration, PSI 2022 The Physiological Society of India (PSI) 2022